Across TCGA patient cohorts, RPA4 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,481 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RPA4-associated proteins across cancer lineages are DIAPH2, GBF1, and WIZ. Each is linked with RPA4 in more than 6 cancer types. Because this analysis shows association rather than direction, both RPA4-to-partner and partner-to-RPA4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RPA4→partner) and Y-score (partner→RPA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	DIAPH2 →	+0.425	+0.636	<.001	<.001	3	7
HNSC	GBF1 →	-0.192	-0.563	<.001	<.001	3	5
LSCC	WIZ →	+0.277	+0.470	<.001	.006	3	4
BRCA	SDC4 →	-0.601	-0.208	<.001	.001	3	4
BRCA	ANP32E →	+0.786	+0.230	<.001	.002	3	4
PDAC	NAXD_Y85 →	+1.133	+0.365	.004	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,481 associations by consensus.

Exploration

RPA4 survival (RNA) · tumor vs normal (RNA) · all RPA4 data types