Across TCGA patient cohorts, RPA4 protein abundance is significantly associated with the RNA expression of many other genes, with 52 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RPA4-associated genes across cancer lineages are LAMA1, BVES, and NFKBIZ. Each is linked with RPA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPA4-to-partner and partner-to-RPA4 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPA4→partner) and Y-score (partner→RPA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LAMA1 →	+3.445	+0.593	<.001	.009	3	1
LSCC	BVES →	+1.835	+0.594	.005	.009	3	1
LSCC	NFKBIZ →	-1.286	-0.593	.006	.009	3	1
LSCC	PMP2 →	+0.734	+0.593	.003	.009	3	1
LSCC	FOS →	-2.196	-0.593	.001	.009	3	1
LSCC	OR9K2 →	-0.072	-0.593	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

Exploration

RPA4 survival (RNA) · tumor vs normal (RNA) · all RPA4 data types