Across TCGA patient cohorts, RPA4 protein abundance is significantly associated with the protein abundance of many other proteins, with 69 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RPA4-associated proteins across cancer lineages are AGFG2, CTTNBP2_S1524, and CTTNBP2NL_S481. Each is linked with RPA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPA4-to-partner and partner-to-RPA4 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RPA4→partner) and Y-score (partner→RPA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	AGFG2 →	-0.565	-0.593	.004	.009	1	1
LSCC	CTTNBP2_S1524 →	+1.548	+0.593	<.001	.009	1	1
LSCC	CTTNBP2NL_S481 →	+0.672	+0.594	.003	.009	1	1
LSCC	CYB561 →	+0.408	+0.594	.007	.009	1	1
LSCC	DDX41_S21 →	-0.656	-0.593	.003	.009	1	1
LSCC	DOCK6_S185 →	-0.966	-0.593	.006	.009	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

Exploration

RPA4 survival (RNA) · tumor vs normal (RNA) · all RPA4 data types