Across TCGA cell cohorts, RPA4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,731 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible RPA4-associated GO terms across cancer lineages are Ribosomal small subunit biogenesis, Maturation of LSU-rRNA, and Positive regulation of telomerase RNA localization to Cajal body. Each is linked with RPA4 in more than 9 cancer types. Because this analysis shows association rather than direction, both RPA4-to-partner and partner-to-RPA4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPA4→partner) and Y-score (partner→RPA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Ribosomal small subunit biogenesis →	+0.162	+0.350	<.001	<.001	3	10
BONE	Maturation of LSU-rRNA →	+0.136	+0.235	<.001	<.001	3	9
BONE	Positive regulation of telomerase RNA localization to Cajal body →	+0.146	+0.351	<.001	<.001	3	8
BONE	Regulation of rRNA processing →	+0.139	+0.330	<.001	.001	3	8
BONE	snRNA pseudouridine synthesis →	+0.131	+0.340	.001	<.001	3	8
BONE	Ribosome biogenesis →	+0.101	+0.229	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,731 associations by consensus.

Exploration

RPA4 survival (RNA) · tumor vs normal (RNA) · all RPA4 data types