RP9

Across TCGA patient cohorts, RP9 mutation is significantly associated with the RNA expression of many other genes, with 544 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RP9-associated genes across cancer lineages are OR2AP1, NOCT, and PLBD2. Each is linked with RP9 in more than 1 cancer types. Because this analysis shows association rather than direction, both RP9-to-partner and partner-to-RP9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2AP1 grouped by RP9-low versus RP9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RP9→partner) and Y-score (partner→RP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OR2AP1 →	+0.048	+3.393	<.001	<.001	3	2
UCEC	NOCT →	+0.905	+3.332	<.001	.005	3	1
UCEC	PLBD2 →	+0.484	+3.483	.005	.002	3	1
UCEC	GPATCH11 →	+0.475	+3.617	.005	.001	3	1
UCEC	SAR1B →	+0.646	+3.483	<.001	.002	3	1
UCEC	TXNDC11 →	+0.409	+3.483	.004	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 544 associations by consensus.

OR2AP1 by RP9 expression — UCEC

Explore this box plot interactively →