RP9

Across TCGA pan-cancer cohorts, RP9 RNA differs between tumor and matched normal tissue in 17 of 18 cancer types tested, making tumor–normal expression one of RP9’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RP9 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RP9 is over-expressed in tumor.

HNSC, KIRC, and COAD are the cancer types where RP9 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RP9 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	IV	+0.882	<.001	12	view →
KIRC	Male	IV	+0.585	<.001	12	view →
COAD	Female	All	+0.967	<.001	11	view →
STAD	Male	II,III,IV	+0.994	<.001	10	view →
BLCA	All	All	+0.841	<.001	10	view →
LIHC	Male	II,III,IV	+1.090	<.001	9	view →
KIRP	All	All	+0.493	<.001	9	view →
LUAD	All	III,IV	+0.613	<.001	8	view →
READ	All	II,III,IV	+0.937	<.001	7	view →
LUSC	Male	All	+0.598	<.001	6	view →
KICH	All	II,III,IV	+0.567	.001	6	view →
THCA	Female	All	+0.256	<.001	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 17 lineages.

RP9–HNSC

Open the HNSC breakdown →