RP9

Across TCGA cell cohorts, RP9 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RP9-associated genes across cancer lineages are CNBD1, CCER1, and BTNL2. Each is linked with RP9 in more than 1 cancer types. Because this analysis shows association rather than direction, both RP9-to-partner and partner-to-RP9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CNBD1 grouped by RP9-low versus RP9-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RP9→partner) and Y-score (partner→RP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CNBD1 →	+0.576	+4.977	<.001	.007	3	1
LARGE_INTESTINE	CCER1 →	+0.012	+4.977	<.001	.007	3	1
LARGE_INTESTINE	BTNL2 →	+0.109	+5.415	<.001	.004	3	1
LARGE_INTESTINE	OR2B3 →	+0.022	+5.415	<.001	.004	3	1
LARGE_INTESTINE	POTEB2 →	+0.012	+5.415	<.001	.004	3	1
BLOOD_Leukemia	IFNA4 →	+0.058	+4.922	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

CNBD1 by RP9 expression — LARGE_INTESTINE

Explore this box plot interactively →