ROR2

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ROR2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,697 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ROR2-associated proteins across cancer lineages are CNN2, CTHRC1, and FBLN1. Each is linked with ROR2 in more than 8 cancer types. Because this analysis shows association rather than direction, both ROR2-to-partner and partner-to-ROR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ROR2 versus CNN2 in GBM, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ROR2→partner) and Y-score (partner→ROR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMCNN2 →+0.622+0.670<.001<.00139
COADCTHRC1 →+1.036+0.925<.001<.00139
OVFBLN1 →+0.693+0.929<.001<.00139
GBMGPX8 →+0.790+0.961<.001<.00139
GBMSULF1 →+1.140+0.867.001.00139
OVTHBS2 →+1.044+0.958<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,697 associations by consensus.

ROR2 vs CNN2 — GBM

Per-sample scatter of ROR2 vs CNN2 in GBM (Pearson r = 0.59).

Explore this scatter interactively →

Exploration