ROR2

Across TCGA cell cohorts, ROR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,307 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ROR2-associated GO terms across cancer lineages are Regulation of postsynaptic membrane potential, Cytoplasmic translation, and Nuclear transport. Each is linked with ROR2 in more than 8 cancer types. Because this analysis shows association rather than direction, both ROR2-to-partner and partner-to-ROR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of postsynaptic membrane potential grouped by ROR2-low versus ROR2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ROR2→partner) and Y-score (partner→ROR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of postsynaptic membrane potential →	-0.156	-1.233	.003	<.001	3	9
OESOPHAGUS	Cytoplasmic translation →	+0.125	+1.507	<.001	<.001	3	9
OESOPHAGUS	Nuclear transport →	+0.084	+1.216	.001	<.001	3	8
OESOPHAGUS	Nucleocytoplasmic transport →	+0.085	+1.216	.001	<.001	3	8
OESOPHAGUS	RNA splicing, via transesterification reactions →	+0.084	+1.369	.006	.002	3	8
OESOPHAGUS	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.084	+1.369	.005	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,307 associations by consensus.

Regulation of postsynaptic membrane potential by ROR2 expression — OESOPHAGUS

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