ROPN1L-AS1

Across TCGA pan-cancer cohorts, ROPN1L-AS1 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated ROPN1L-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher ROPN1L-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ROPN1L-AS1 expression acts as an unfavorable survival marker, although some lineages such as OV and PAAD show a favorable association.

ACC, KIRP, and COAD are the cancer types where ROPN1L-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	III,IV	0.390	0.821	<.001	81	view →
KIRP	DFS	Median	All	0.841	0.959	<.001	51	view →
COAD	DFS	Tertile	IV	0.250	0.514	.007	36	view →
LUSC	OS	Tertile	IV	0.001	0.673	.014	36	view →
CHOL	OS	Tertile	II,III,IV	0.019	0.765	.001	27	view →
OV	OS	Median	All	0.892	0.798	.006	22	view →
TGCT	DFS	Tertile	II,III,IV	0.621	0.949	.034	18	view →
BLCA	DFS	Tertile	III,IV	0.430	0.563	.040	9	view →
PAAD	DFS	Tertile	All	0.649	0.318	.029	6	view →
KIRC	DFS	Quartile	IV	0.344	0.604	.023	6	view →
LUAD	DFS	Quartile	IV	1.000	0.408	.018	6	view →
LIHC	OS	Tertile	III,IV	0.420	0.673	.024	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

ROPN1L-AS1–ACC (OS)

Open the ACC breakdown →