ROPN1L-AS1

Across TCGA pan-cancer cohorts, ROPN1L-AS1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of ROPN1L-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where ROPN1L-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ROPN1L-AS1 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KICH, KIRP, and LUSC are the cancer types where ROPN1L-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ROPN1L-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	−0.395	.001	6	view →
KIRP	All	III,IV	+0.234	.027	3	view →
LUSC	Male	All	+0.128	.019	2	view →
HNSC	Male	All	+0.059	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

ROPN1L-AS1–KICH

Open the KICH breakdown →