ROPN1B

Across TCGA patient cohorts, ROPN1B mutation is significantly associated with the RNA expression of many other genes, with 798 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ROPN1B-associated genes across cancer lineages are RNU6-74P, LINC01848, and MIR3621. Each is linked with ROPN1B in more than 1 cancer types. Because this analysis shows association rather than direction, both ROPN1B-to-partner and partner-to-ROPN1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-74P grouped by ROPN1B-low versus ROPN1B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ROPN1B→partner) and Y-score (partner→ROPN1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-74P →	+0.387	+3.428	.003	.007	3	2
COAD	LINC01848 →	+0.087	+3.665	<.001	.004	3	2
COAD	MIR3621 →	+0.309	+4.595	<.001	.004	3	2
UCEC	NPLP1 →	+0.182	+1.791	<.001	.007	3	2
UCEC	IGHEP2 →	+0.154	+4.379	.006	<.001	3	2
UCEC	CRYBB2P1 →	+0.596	+3.764	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 798 associations by consensus.

RNU6-74P by ROPN1B expression — COAD

Explore this box plot interactively →