ROPN1

Across TCGA patient cohorts, ROPN1 mutation is significantly associated with the RNA expression of many other genes, with 3,912 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ROPN1-associated genes across cancer lineages are RNA5SP86, RN7SKP25, and RNU6-425P. Each is linked with ROPN1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ROPN1-to-partner and partner-to-ROPN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP86 grouped by ROPN1-low versus ROPN1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ROPN1→partner) and Y-score (partner→ROPN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNA5SP86 →	+0.829	+4.821	<.001	.003	3	3
BLCA	RN7SKP25 →	+0.286	+4.208	<.001	.009	3	2
COAD	RNU6-425P →	+0.672	+4.399	<.001	.006	3	2
UCEC	H4C1 →	+0.655	+1.662	<.001	.004	3	2
UCEC	RNU1-1 →	+0.153	+1.863	.002	.008	3	2
UCEC	RNU6-5P →	+0.430	+1.549	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,912 associations by consensus.

RNA5SP86 by ROPN1 expression — COAD

Explore this box plot interactively →