ROPN1

Across TCGA cell cohorts, ROPN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,103 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ROPN1-associated GO terms across cancer lineages are Endosomal lumen acidification, Negative regulation of chromosome organization, and Viral gene expression. Each is linked with ROPN1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ROPN1-to-partner and partner-to-ROPN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal lumen acidification grouped by ROPN1-low versus ROPN1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ROPN1→partner) and Y-score (partner→ROPN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Endosomal lumen acidification →	+0.124	+2.636	<.001	<.001	3	6
BLOOD_Leukemia	Negative regulation of chromosome organization →	+0.035	+0.022	.003	.002	3	5
KIDNEY	Viral gene expression →	+0.077	+0.062	.001	.005	3	5
SKIN	Phosphatidylinositol phosphate biosynthetic process →	+0.036	+1.664	<.001	<.001	3	5
SKIN	Vesicle fusion →	+0.030	+1.174	.002	.009	3	5
SKIN	Lysosome organization →	+0.048	+1.756	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,103 associations by consensus.

Endosomal lumen acidification by ROPN1 expression — SKIN

Explore this box plot interactively →