Across TCGA patient cohorts, ROBO2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,883 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ROBO2-associated genes across cancer lineages are RSPH1, PGR, and VDAC1P7. Each is linked with ROBO2 in more than 3 cancer types. Because this analysis shows association rather than direction, both ROBO2-to-partner and partner-to-ROBO2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ROBO2→partner) and Y-score (partner→ROBO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RSPH1 →	+1.792	+0.646	<.001	<.001	3	4
BRCA	PGR →	+2.006	+0.920	.004	.003	3	4
UCEC	VDAC1P7 →	+1.284	+0.690	<.001	<.001	3	4
LUAD	CDC25B →	-0.770	-0.434	.003	.006	3	3
UCEC	DNAH7 →	+0.704	+0.404	.003	.008	3	3
BRCA	BMPR1B →	+2.649	+0.986	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,883 associations by consensus.

Exploration

ROBO2 survival (RNA) · tumor vs normal (RNA) · all ROBO2 data types