ROBO1

Across TCGA patient cohorts, ROBO1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,845 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ROBO1-associated genes across cancer lineages are RN7SL751P, PLS1, and COL1A2. Each is linked with ROBO1 in more than 6 cancer types. Because this analysis shows association rather than direction, both ROBO1-to-partner and partner-to-ROBO1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ROBO1 versus RN7SL751P in LSCC, with a Pearson correlation of 0.84.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ROBO1→partner) and Y-score (partner→ROBO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RN7SL751P →	+1.201	+0.624	<.001	<.001	3	7
HNSC	PLS1 →	-0.763	-0.222	.004	.008	3	4
CCRCC	COL1A2 →	+1.702	+0.566	<.001	<.001	3	4
UCEC	GPC6-AS2 →	+0.972	+0.389	<.001	<.001	3	4
CCRCC	COL6A3 →	+1.314	+0.405	.003	.009	3	4
LSCC	TWIST1 →	+0.944	+0.359	.006	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,845 associations by consensus.

ROBO1 vs RN7SL751P — LSCC

Explore this scatter interactively →