RNY4

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RNY4 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RNY4’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where RNY4 RNA is repressed in tumor relative to normal tissue. In most cancer types RNY4 is over-expressed in tumor, although a few such as STAD and KICH show the opposite, repressed pattern.

STAD and KICH are the cancer types where RNY4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNY4 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
STADMaleAll−0.856.0234view →
KICHAllII,III,IV−0.192.0411view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

RNY4–STAD

Tumor-vs-normal expression box plot for RNY4 RNA in STAD.

Open the STAD breakdown →

Exploration