Across TCGA pan-cancer cohorts, RNY3P13 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RNY3P13’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where RNY3P13 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNY3P13 is over-expressed in tumor.
BRCA and STAD are the cancer types where RNY3P13 tumor–normal differential expression is most reproducible.