RNVU1-2A

Across TCGA pan-cancer cohorts, RNVU1-2A RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated RNVU1-2A data layer.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher RNVU1-2A RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNVU1-2A expression acts as an unfavorable survival marker, although some lineages such as ESCA and CESC show a favorable association.

TGCT, UVM, and HNSC are the cancer types where RNVU1-2A RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
TGCT	OS	Tertile	II,III,IV	0.501	0.996	<.001	54	view →
UVM	OS	Tertile	All	0.136	0.919	<.001	45	view →
HNSC	DFS	Tertile	All	0.507	0.642	.003	42	view →
READ	DFS	Tertile	III,IV	0.382	0.802	<.001	42	view →
LAML	DFS	Median	All	0.309	0.717	<.001	26	view →
LUSC	OS	Tertile	III,IV	0.224	0.735	.004	24	view →
KIRC	DFS	Tertile	All	0.338	0.652	.022	18	view →
ACC	OS	Tertile	All	0.557	0.892	.003	18	view →
LUAD	DFS	Tertile	IV	0.370	0.702	.045	18	view →
ESCA	DFS	Median	II,III,IV	1.000	0.452	.023	14	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	12	view →
THYM	DFS	Tertile	II,III,IV	0.172	0.747	.005	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

RNVU1-2A–TGCT (OS)

Open the TGCT breakdown →