RNVU1-2A

Across TCGA pan-cancer cohorts, RNVU1-2A RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNVU1-2A’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RNVU1-2A RNA is repressed in tumor relative to normal tissue. In most cancer types RNVU1-2A is over-expressed in tumor, although a few such as THCA and STAD show the opposite, repressed pattern.

THCA, HNSC, and LUAD are the cancer types where RNVU1-2A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNVU1-2A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	All	−1.417	<.001	11	view →
HNSC	Male	All	+0.107	.017	4	view →
LUAD	All	All	+0.547	.017	1	view →
STAD	Male	IV	−0.515	<.001	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RNVU1-2A–THCA

Open the THCA breakdown →