RNVU1-21

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNVU1-21 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated RNVU1-21 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNVU1-21 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNVU1-21 expression acts as an unfavorable survival marker, although some lineages such as PAAD and SKCM show a favorable association.

KIRC, BRCA, and PAAD are the cancer types where RNVU1-21 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCDFSMedianAll0.5410.695<.00150view →
BRCADFSTertileAll0.4810.609<.00146view →
PAADDFSMedianAll0.3980.143<.00144view →
KIRPOSQuartileAll0.8590.987.00244view →
UVMOSMedianAll0.3820.890<.00134view →
COADOSQuartileAll0.4740.690.00821view →
LIHCOSQuartileAll0.5820.721.00720view →
SKCMOSTertileAll0.3930.271.00414view →
LUADOSTertileAll0.5190.292.00412view →
KICHDFSMedianII,III,IV0.6791.000.02212view →
PCPGDFSMedianAll1.0000.682.00212view →
OVDFSMedianII,III,IV0.1320.193.01510view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

Exploration