Across TCGA pan-cancer cohorts, RNVU1-21 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of RNVU1-21’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where RNVU1-21 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNVU1-21 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.
LUAD, LUSC, and BLCA are the cancer types where RNVU1-21 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNVU1-21 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.