RNVU1-2

Across TCGA pan-cancer cohorts, RNVU1-2 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RNVU1-2 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RNVU1-2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNVU1-2 expression acts as an unfavorable survival marker, although some lineages such as PAAD and STAD show a favorable association.

ACC, UVM, and HNSC are the cancer types where RNVU1-2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.156	0.724	.002	54	view →
UVM	OS	Tertile	All	0.213	0.696	.004	45	view →
HNSC	OS	Tertile	IV	0.361	0.672	.004	30	view →
PAAD	DFS	Tertile	II,III,IV	0.676	0.410	.024	27	view →
UCS	OS	Tertile	III,IV	0.272	0.623	.016	24	view →
CHOL	OS	Tertile	All	0.280	0.734	.002	21	view →
STAD	OS	Median	IV	0.631	0.347	.015	17	view →
LAML	DFS	Quartile	All	0.520	0.230	.018	16	view →
SKCM	OS	Tertile	All	0.463	0.296	.005	12	view →
GBM	DFS	Tertile	All	0.203	0.364	.025	8	view →
THCA	OS	Tertile	IV	0.720	1.000	.004	6	view →
LIHC	OS	Tertile	III,IV	0.860	0.606	.043	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

RNVU1-2–ACC (OS)

Open the ACC breakdown →