RNVU1-2

Across TCGA pan-cancer cohorts, RNVU1-2 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNVU1-2’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RNVU1-2 RNA is repressed in tumor relative to normal tissue. In most cancer types RNVU1-2 is over-expressed in tumor, although a few such as THCA and HNSC show the opposite, repressed pattern.

THCA, HNSC, and COAD are the cancer types where RNVU1-2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNVU1-2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	IV	−1.926	<.001	11	view →
HNSC	Female	III,IV	−0.205	.032	3	view →
COAD	All	II,III,IV	+0.205	.016	3	view →
KIRP	All	All	−0.116	.006	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RNVU1-2–THCA

Open the THCA breakdown →