RNU7-59P

Across TCGA pan-cancer cohorts, RNU7-59P RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated RNU7-59P data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher RNU7-59P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU7-59P expression acts as an unfavorable survival marker, although some lineages such as OV and LUAD show a favorable association.

THCA, KICH, and DLBC are the cancer types where RNU7-59P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Tertile	IV	0.392	0.868	<.001	90	view →
KICH	DFS	Tertile	All	0.541	0.922	<.001	69	view →
DLBC	OS	Tertile	II,III,IV	0.586	0.899	<.001	63	view →
SKCM	OS	Tertile	IV	0.213	0.775	<.001	54	view →
LGG	OS	Quartile	All	0.705	0.834	<.001	25	view →
OV	OS	Median	II,III,IV	0.370	0.268	.009	20	view →
MESO	OS	Tertile	IV	0.243	0.646	.042	18	view →
COAD	DFS	Tertile	IV	0.099	0.515	.010	18	view →
CESC	OS	Tertile	III,IV	0.229	0.676	.028	18	view →
LUAD	OS	Tertile	III,IV	1.000	0.618	.016	12	view →
LUSC	DFS	Tertile	II,III,IV	0.159	0.581	<.001	12	view →
CHOL	DFS	Tertile	III,IV	0.118	0.476	.031	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

RNU7-59P–THCA (DFS)

Open the THCA breakdown →