RNU7-59P

Across TCGA pan-cancer cohorts, RNU7-59P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RNU7-59P’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RNU7-59P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU7-59P is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

HNSC, THCA, and LUAD are the cancer types where RNU7-59P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU7-59P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.275	.001	5	view →
THCA	Female	All	−0.321	.005	4	view →
LUAD	Male	II,III,IV	+0.433	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

RNU7-59P–HNSC

Open the HNSC breakdown →