RNU7-53P

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNU7-53P RNA expression is significantly associated with the go_rna of many other GO terms, with 2,407 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU7-53P-associated GO terms across cancer lineages are Positive regulation of proteasomal protein catabolic process, Positive regulation of proteolysis involved in protein catabolic process, and Positive regulation of extrinsic apoptotic signaling pathway. Each is linked with RNU7-53P in more than 3 cancer types. Because this analysis shows association rather than direction, both RNU7-53P-to-partner and partner-to-RNU7-53P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of proteasomal protein catabolic process grouped by RNU7-53P-low versus RNU7-53P-high in BRCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU7-53P→partner) and Y-score (partner→RNU7-53P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAPositive regulation of proteasomal protein catabolic process →+0.075+0.032<.001.00133
BRCAPositive regulation of proteolysis involved in protein catabolic process →+0.071+0.027<.001.00324
STADPositive regulation of extrinsic apoptotic signaling pathway →+0.065+0.158<.001<.00133
BRCAPositive regulation of binding →+0.075+0.032<.001<.00133
BRCARegulation of proteasomal protein catabolic process →+0.078+0.026<.001.00333
BRCA'de novo' protein folding →+0.079+0.020<.001.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,407 associations by consensus.

Positive regulation of proteasomal protein catabolic process by RNU7-53P expression — BRCA

Box plot of Positive regulation of proteasomal protein catabolic process in RNU7-53P-low vs RNU7-53P-high samples in BRCA.

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