RNU7-53P

Across TCGA pan-cancer cohorts, RNU7-53P RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated RNU7-53P data layer.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher RNU7-53P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU7-53P expression acts as an unfavorable survival marker.

ESCA, STAD, and LUSC are the cancer types where RNU7-53P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Tertile	IV	0.095	0.512	.008	54	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	27	view →
LUSC	DFS	Tertile	All	0.222	0.750	<.001	18	view →
PCPG	DFS	Tertile	All	0.063	0.924	<.001	18	view →
READ	DFS	Tertile	III,IV	0.082	0.746	<.001	18	view →
SARC	OS	Tertile	All	0.241	0.766	.022	9	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

RNU7-53P–ESCA (OS)

Open the ESCA breakdown →