RNU7-4P

Across TCGA pan-cancer cohorts, RNU7-4P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNU7-4P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU7-4P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RNU7-4P expression acts as an unfavorable survival marker, although some lineages such as KIRC and LUAD show a favorable association.

KIRC, CHOL, and LUSC are the cancer types where RNU7-4P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.778	0.596	.001	144	view →
CHOL	OS	Tertile	All	0.087	0.836	<.001	54	view →
LUSC	DFS	Tertile	II,III,IV	0.150	0.417	.002	39	view →
COAD	OS	Tertile	IV	0.244	0.662	.015	33	view →
THYM	OS	Tertile	All	0.381	0.879	.003	24	view →
STAD	DFS	Quartile	All	0.204	0.403	.013	23	view →
THCA	DFS	Tertile	II,III,IV	0.116	0.878	<.001	18	view →
LUAD	DFS	Tertile	III,IV	0.492	0.251	.030	12	view →
PRAD	OS	Tertile	All	0.957	0.996	<.001	12	view →
SARC	OS	Tertile	All	0.233	0.607	.030	12	view →
SKCM	OS	Tertile	III,IV	0.250	0.801	<.001	9	view →
OV	OS	Tertile	IV	0.864	0.582	.023	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

RNU7-4P–KIRC (DFS)

Open the KIRC breakdown →