RNU7-46P

Across TCGA pan-cancer cohorts, RNU7-46P RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated RNU7-46P data layer.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher RNU7-46P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU7-46P expression acts as an unfavorable survival marker, although some lineages such as OV show a favorable association.

ESCA, BRCA, and PAAD are the cancer types where RNU7-46P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Tertile	All	0.471	0.906	.031	36	view →
BRCA	OS	Tertile	All	0.816	0.927	.005	30	view →
PAAD	OS	Tertile	All	0.200	0.589	.006	27	view →
READ	OS	Tertile	All	0.069	0.910	<.001	27	view →
SKCM	OS	Tertile	II,III,IV	0.241	0.845	<.001	18	view →
OV	OS	Tertile	III,IV	0.875	0.829	.048	6	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

RNU7-46P–ESCA (OS)

Open the ESCA breakdown →