RNU7-43P

Across TCGA pan-cancer cohorts, RNU7-43P RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RNU7-43P data layer.

The strongest signal is observed in mesothelioma (MESO), where higher RNU7-43P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU7-43P expression acts as an unfavorable survival marker, although some lineages such as BRCA and LGG show a favorable association.

MESO, COAD, and BLCA are the cancer types where RNU7-43P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	All	0.260	0.427	.016	36	view →
COAD	DFS	Tertile	III,IV	0.438	0.684	.012	24	view →
BLCA	OS	Tertile	All	0.531	0.731	.021	19	view →
BRCA	DFS	Tertile	III,IV	0.881	0.764	.032	18	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
KIRC	DFS	Quartile	All	0.523	0.654	.031	15	view →
THCA	OS	Tertile	IV	0.559	0.932	.003	14	view →
UCEC	DFS	Tertile	All	0.420	0.684	.025	12	view →
LGG	DFS	Quartile	All	0.835	0.692	.016	7	view →
PCPG	DFS	Quartile	All	0.803	0.909	.032	5	view →
LAML	DFS	Tertile	All	0.501	0.344	.045	4	view →
SKCM	DFS	Tertile	All	0.100	0.251	.023	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

RNU7-43P–MESO (OS)

Open the MESO breakdown →