RNU7-43P

Across TCGA pan-cancer cohorts, RNU7-43P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU7-43P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where RNU7-43P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU7-43P is over-expressed in tumor, although a few such as KIRP and LUSC show the opposite, repressed pattern.

KIRP, KICH, and LUSC are the cancer types where RNU7-43P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU7-43P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	II,III,IV	−0.559	.011	6	view →
KICH	Female	III,IV	+0.656	<.001	2	view →
LUSC	Female	All	−0.491	.010	2	view →
CHOL	Female	All	+1.233	.004	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RNU7-43P–KIRP

Open the KIRP breakdown →