RNU7-18P

Across TCGA pan-cancer cohorts, RNU7-18P RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNU7-18P data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher RNU7-18P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU7-18P expression acts as an unfavorable survival marker, although some lineages such as STAD and BRCA show a favorable association.

UVM, THCA, and GBM are the cancer types where RNU7-18P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	III,IV	0.174	0.716	<.001	117	view →
THCA	DFS	Tertile	All	0.768	0.924	<.001	66	view →
GBM	OS	Tertile	All	0.131	0.433	.001	54	view →
KICH	DFS	Quartile	II,III,IV	0.397	0.869	.001	39	view →
LGG	OS	Tertile	All	0.778	0.912	<.001	36	view →
KIRC	DFS	Tertile	II,III,IV	0.418	0.572	.008	35	view →
MESO	OS	Tertile	II,III,IV	0.217	0.645	.008	27	view →
STAD	OS	Median	All	0.639	0.484	.005	22	view →
READ	DFS	Tertile	IV	0.141	0.671	<.001	18	view →
ESCA	DFS	Median	II,III,IV	0.396	0.580	.009	15	view →
UCEC	DFS	Tertile	III,IV	0.707	0.808	.023	6	view →
PCPG	OS	Tertile	All	0.865	1.000	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

RNU7-18P–UVM (DFS)

Open the UVM breakdown →