RNU7-154P

Across TCGA pan-cancer cohorts, RNU7-154P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU7-154P’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where RNU7-154P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU7-154P is over-expressed in tumor, although a few such as BRCA and CHOL show the opposite, repressed pattern.

BRCA, LUSC, and CHOL are the cancer types where RNU7-154P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU7-154P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	−0.277	.007	2	view →
LUSC	Female	III,IV	+1.395	.029	1	view →
CHOL	Male	All	−0.976	.012	1	view →
LUSC	Male	All	−0.333	.048	1	view →
KIRC	All	IV	+0.256	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 4 lineages.

RNU7-154P–BRCA

Open the BRCA breakdown →