RNU7-140P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU7-140P RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated RNU7-140P data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RNU7-140P RNA is associated with better overall survival. In most high-consensus cancer types, elevated RNU7-140P expression acts as an unfavorable survival marker, although some lineages such as BRCA and UCS show a favorable association.

BRCA, UCS, and ACC are the cancer types where RNU7-140P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCAOSTertileIII,IV0.9430.743<.00132view →
UCSDFSMedianIV0.9520.367.00124view →
ACCDFSMedianIV0.1550.535.00122view →
KIRCDFSTertileAll0.4810.711.00114view →
BLCAOSTertileIV0.1600.561.0169view →
CHOLDFSMedianII,III,IV0.6900.151.0049view →
LUADDFSQuartileII,III,IV0.5590.233.0069view →
LGGDFSTertileAll0.3800.500.0139view →
ESCADFSQuartileIII,IV0.2360.488.0139view →
PRADOSQuartileAll0.9671.000.0328view →
COADOSQuartileAll0.8270.898.0207view →
PAADDFSQuartileAll0.5360.279.0186view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

RNU7-140P–BRCA (OS)

Kaplan–Meier survival curve for RNU7-140P RNA-high vs -low samples in BRCA.

Open the BRCA breakdown →

Exploration