RNU7-140P

Across TCGA pan-cancer cohorts, RNU7-140P RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of RNU7-140P’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where RNU7-140P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU7-140P is over-expressed in tumor, although a few such as COAD and KIRC show the opposite, repressed pattern.

LUSC, COAD, and CHOL are the cancer types where RNU7-140P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU7-140P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	+0.489	.009	5	view →
COAD	All	III,IV	−0.969	.008	4	view →
CHOL	Female	All	+2.083	<.001	2	view →
ESCA	All	II,III,IV	+1.375	.004	2	view →
KIRC	Female	IV	−0.874	.008	1	view →
KICH	All	II,III,IV	+0.541	.036	1	view →
HNSC	Male	III,IV	+0.539	.018	1	view →
LUAD	Female	All	+0.466	.041	1	view →
KIRC	All	All	+0.260	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 8 lineages.

RNU7-140P–LUSC

Open the LUSC breakdown →