RNU7-12P

Across TCGA pan-cancer cohorts, RNU7-12P RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNU7-12P data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher RNU7-12P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU7-12P expression acts as an unfavorable survival marker, although some lineages such as LUSC show a favorable association.

OV, READ, and UCEC are the cancer types where RNU7-12P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Quartile	All	0.755	0.867	<.001	120	view →
READ	OS	Tertile	All	0.188	0.666	<.001	99	view →
UCEC	DFS	Tertile	III,IV	0.630	0.809	.003	78	view →
LIHC	OS	Tertile	III,IV	0.178	0.661	<.001	45	view →
ESCA	DFS	Tertile	II,III,IV	0.364	1.000	.009	42	view →
PAAD	OS	Tertile	All	0.300	0.622	<.001	36	view →
ACC	DFS	Tertile	III,IV	0.039	0.381	.008	33	view →
LGG	OS	Tertile	All	0.565	0.823	<.001	33	view →
BRCA	DFS	Tertile	II,III,IV	0.279	0.537	.001	30	view →
KIRC	OS	Tertile	All	0.502	0.649	.027	21	view →
DLBC	DFS	Tertile	III,IV	0.137	0.790	<.001	18	view →
UCS	DFS	Tertile	All	0.195	0.542	.011	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

RNU7-12P–OV (OS)

Open the OV breakdown →