RNU7-12P

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU7-12P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RNU7-12P’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where RNU7-12P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU7-12P is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.

STAD, BLCA, and COAD are the cancer types where RNU7-12P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU7-12P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
STADMaleAll+0.814<.0016view →
BLCAAllAll+0.521.0095view →
COADAllII,III,IV−0.112.0422view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

RNU7-12P–STAD

Tumor-vs-normal expression box plot for RNU7-12P RNA in STAD.

Open the STAD breakdown →

Exploration