RNU7-115P

Across TCGA patient cohorts, RNU7-115P mutation is significantly associated with the RNA expression of many other genes, with 55 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNU7-115P-associated genes across cancer lineages are MTCO3P42, MIR548A1, and MIR3651. Each is linked with RNU7-115P in more than 1 cancer types. Because this analysis shows association rather than direction, both RNU7-115P-to-partner and partner-to-RNU7-115P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTCO3P42 grouped by RNU7-115P-low versus RNU7-115P-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU7-115P→partner) and Y-score (partner→RNU7-115P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MTCO3P42 →	+0.070	+4.362	<.001	.001	3	2
UCEC	MIR548A1 →	+0.380	+4.464	<.001	.005	3	2
UCEC	MIR3651 →	+0.792	+3.496	<.001	.001	3	1
SKCM	MRPS18BP2 →	+0.072	+3.533	<.001	.007	3	1
SKCM	GEMIN2P2 →	+0.047	+3.408	<.001	.009	3	1
SKCM	TSPY12P →	+0.060	+5.219	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 55 associations by consensus.

MTCO3P42 by RNU7-115P expression — SKCM

Explore this box plot interactively →