RNU6-991P

Across TCGA patient cohorts, RNU6-991P RNA expression is significantly associated with the go_rna of many other GO terms, with 6,419 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-991P-associated GO terms across cancer lineages are Macromolecule methylation, Protein-containing complex localization, and Positive regulation of double-strand break repair. Each is linked with RNU6-991P in more than 9 cancer types. Because this analysis shows association rather than direction, both RNU6-991P-to-partner and partner-to-RNU6-991P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macromolecule methylation grouped by RNU6-991P-low versus RNU6-991P-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-991P→partner) and Y-score (partner→RNU6-991P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Macromolecule methylation →	+0.107	+0.208	<.001	<.001	3	10
STAD	Protein-containing complex localization →	+0.083	+0.293	<.001	<.001	3	10
STAD	Positive regulation of double-strand break repair →	+0.100	+0.283	<.001	<.001	3	9
STAD	Polysaccharide metabolic process →	+0.072	+0.289	<.001	<.001	3	9
STAD	Glucose metabolic process →	+0.097	+0.306	<.001	<.001	3	9
STAD	Protein methylation →	+0.096	+0.295	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,419 associations by consensus.

Macromolecule methylation by RNU6-991P expression — ESCA

Explore this box plot interactively →