RNU6-991P

Across TCGA pan-cancer cohorts, RNU6-991P RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated RNU6-991P data layer.

The strongest signal is observed in mesothelioma (MESO), where higher RNU6-991P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-991P expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

MESO, LUSC, and ACC are the cancer types where RNU6-991P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	III,IV	0.117	0.582	<.001	153	view →
LUSC	OS	Tertile	All	0.324	0.681	.003	72	view →
ACC	OS	Tertile	All	0.114	0.892	<.001	72	view →
UCEC	OS	Tertile	III,IV	0.574	0.840	.001	66	view →
THYM	OS	Tertile	All	0.557	0.987	<.001	51	view →
BLCA	DFS	Tertile	All	0.180	0.627	.004	36	view →
KIRC	DFS	Tertile	II,III,IV	0.423	0.690	.011	30	view →
LUAD	DFS	Tertile	All	0.731	0.323	.015	18	view →
SKCM	DFS	Tertile	II,III,IV	0.192	0.564	.015	15	view →
CHOL	OS	Tertile	All	0.155	0.725	.029	9	view →
PRAD	DFS	Tertile	All	0.796	0.892	.045	6	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

RNU6-991P–MESO (OS)

Open the MESO breakdown →