RNU6-977P

Across TCGA pan-cancer cohorts, RNU6-977P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU6-977P’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where RNU6-977P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-977P is over-expressed in tumor, although a few such as UCEC and ESCA show the opposite, repressed pattern.

UCEC, BRCA, and ESCA are the cancer types where RNU6-977P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-977P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	All	−0.182	.041	2	view →
BRCA	Female	All	+0.155	.027	2	view →
ESCA	Female	All	−1.683	.005	1	view →
THCA	All	All	−0.130	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RNU6-977P–UCEC

Open the UCEC breakdown →