RNU6-95P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-95P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated RNU6-95P data layer.

The strongest signal is observed in mesothelioma (MESO), where higher RNU6-95P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-95P expression acts as an unfavorable survival marker.

MESO, KIRP, and THCA are the cancer types where RNU6-95P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
MESOOSTertileIII,IV0.0770.580<.001126view →
KIRPOSTertileII,III,IV0.1050.582.00430view →
THCAOSTertileII,III,IV0.2730.892<.00127view →
PCPGOSTertileAll0.1420.963<.00127view →
DLBCDFSTertileAll0.0220.809<.00118view →
SARCOSTertileAll0.0220.861<.00118view →
GBMDFSTertileAll0.0600.242.0169view →
SKCMOSTertileAll0.4910.788.0186view →
ESCADFSQuartileAll0.2200.384.0303view →
LGGOSTertileAll0.5700.893.0043view →
Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

Exploration