RNU6-958P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-958P RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated RNU6-958P data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RNU6-958P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-958P expression acts as an unfavorable survival marker.

BRCA, MESO, and KIRC are the cancer types where RNU6-958P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCADFSTertileII,III,IV0.7210.894<.00154view →
MESOOSTertileII,III,IV0.1210.571.00454view →
KIRCOSTertileII,III,IV0.1520.560.00551view →
SKCMDFSTertileAll0.0580.757<.00136view →
LUSCOSTertileII,III,IV0.2940.737.00136view →
STADOSTertileIII,IV0.4740.669.02026view →
LIHCOSTertileII,III,IV0.2260.769.00818view →
SARCDFSTertileAll0.1820.594.0319view →
ESCADFSQuartileAll0.3120.784.0304view →
Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

RNU6-958P–BRCA (DFS)

Kaplan–Meier survival curve for RNU6-958P RNA-high vs -low samples in BRCA.

Open the BRCA breakdown →

Exploration