RNU6-943P

Across TCGA pan-cancer cohorts, RNU6-943P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU6-943P’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where RNU6-943P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-943P is over-expressed in tumor, although a few such as BRCA and LUAD show the opposite, repressed pattern.

BRCA, LUAD, and LUSC are the cancer types where RNU6-943P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-943P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	III,IV	−0.525	<.001	6	view →
LUAD	Female	II,III,IV	−0.648	.001	5	view →
LUSC	Female	All	−0.538	.008	2	view →
KIRC	All	All	−0.032	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RNU6-943P–BRCA

Open the BRCA breakdown →