RNU6-911P

Across TCGA pan-cancer cohorts, RNU6-911P RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated RNU6-911P data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher RNU6-911P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-911P expression acts as an unfavorable survival marker, although some lineages such as HNSC and CESC show a favorable association.

SKCM, ACC, and THCA are the cancer types where RNU6-911P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Tertile	All	0.324	0.631	<.001	129	view →
ACC	DFS	Tertile	All	0.046	0.753	<.001	72	view →
THCA	OS	Quartile	II,III,IV	0.750	1.000	.002	35	view →
UCS	OS	Quartile	All	0.488	0.722	.027	34	view →
KIRC	OS	Tertile	All	0.410	0.643	<.001	33	view →
LGG	DFS	Tertile	All	0.647	0.840	.002	33	view →
HNSC	OS	Tertile	All	0.851	0.731	.003	32	view →
COAD	DFS	Tertile	II,III,IV	0.485	0.761	.004	30	view →
CESC	DFS	Median	All	0.643	0.433	<.001	30	view →
LIHC	OS	Tertile	II,III,IV	0.213	0.715	.020	27	view →
LUSC	DFS	Median	All	0.802	0.710	.015	25	view →
SARC	DFS	Tertile	All	0.073	0.610	<.001	24	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

RNU6-911P–SKCM (DFS)

Open the SKCM breakdown →