RNU6-911P

Across TCGA pan-cancer cohorts, RNU6-911P RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of RNU6-911P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where RNU6-911P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-911P is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

KICH, KIRC, and THCA are the cancer types where RNU6-911P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-911P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	All	−1.510	<.001	10	view →
KIRC	Female	II,III,IV	−1.107	<.001	10	view →
THCA	All	II,III,IV	−0.899	<.001	7	view →
LUAD	Female	All	−0.473	.001	5	view →
BLCA	All	All	+0.323	.013	4	view →
READ	All	III,IV	+1.170	<.001	2	view →
LUSC	All	II,III,IV	+0.492	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

RNU6-911P–KICH

Open the KICH breakdown →