RNU6-89P

Across TCGA pan-cancer cohorts, RNU6-89P RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated RNU6-89P data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RNU6-89P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-89P expression acts as an unfavorable survival marker, although some lineages such as ESCA and LAML show a favorable association.

HNSC, ACC, and ESCA are the cancer types where RNU6-89P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.131	0.687	.001	108	view →
ACC	OS	Tertile	All	0.113	0.822	<.001	63	view →
ESCA	OS	Quartile	III,IV	0.733	0.308	<.001	46	view →
LIHC	OS	Tertile	All	0.122	0.704	.009	27	view →
CESC	DFS	Tertile	IV	0.053	0.529	<.001	18	view →
GBM	DFS	Tertile	All	0.066	0.257	.019	18	view →
BRCA	DFS	Tertile	II,III,IV	0.220	0.532	.002	12	view →
PRAD	OS	Tertile	All	0.966	0.995	.023	12	view →
STAD	DFS	Tertile	IV	0.097	0.412	.008	9	view →
LAML	DFS	Quartile	All	0.564	0.378	.045	4	view →
SKCM	DFS	Tertile	All	1.000	0.198	.040	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

RNU6-89P–HNSC (OS)

Open the HNSC breakdown →