RNU6-88P

Across TCGA pan-cancer cohorts, RNU6-88P RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated RNU6-88P data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher RNU6-88P RNA is associated with better overall survival. In most high-consensus cancer types, elevated RNU6-88P expression acts as an unfavorable survival marker, although some lineages such as SKCM and UCS show a favorable association.

SKCM, UCS, and KIRC are the cancer types where RNU6-88P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Quartile	III,IV	0.648	0.324	.002	38	view →
UCS	DFS	Tertile	IV	0.711	0.239	.024	24	view →
KIRC	OS	Median	II,III,IV	0.409	0.594	.009	20	view →
READ	OS	Median	II,III,IV	0.792	0.493	.006	20	view →
UVM	DFS	Tertile	III,IV	0.343	0.698	.006	13	view →
LUAD	OS	Median	II,III,IV	0.766	0.647	.019	13	view →
LUSC	OS	Tertile	III,IV	0.847	0.487	.006	13	view →
ACC	DFS	Tertile	All	0.973	0.577	.004	13	view →
DLBC	DFS	Quartile	All	0.377	1.000	.015	9	view →
COAD	DFS	Median	IV	0.613	0.375	.004	9	view →
KIRP	DFS	Median	III,IV	0.153	0.570	.013	8	view →
LGG	DFS	Quartile	All	0.738	0.858	.003	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

RNU6-88P–SKCM (OS)

Open the SKCM breakdown →