RNU6-88P

Across TCGA pan-cancer cohorts, RNU6-88P RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of RNU6-88P’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where RNU6-88P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-88P is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

UCEC, THCA, and KIRC are the cancer types where RNU6-88P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-88P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	III,IV	+1.474	<.001	6	view →
THCA	Female	All	−0.558	<.001	6	view →
KIRC	All	All	+0.378	<.001	5	view →
LUSC	All	All	+0.471	.002	4	view →
HNSC	All	All	+0.360	<.001	4	view →
BLCA	All	All	+0.492	.030	2	view →
LUAD	All	All	+0.362	.009	2	view →
BRCA	All	All	+0.274	.014	2	view →
COAD	Female	IV	+1.234	.001	1	view →
STAD	All	All	+0.503	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

RNU6-88P–UCEC

Open the UCEC breakdown →